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Mitotic spindle (DIS)orientation and DISease: Cause or consequence?

Correct alignment of the mitotic spindle during cell division is crucial for cell fate determination, tissue organization, and development. Mutations causing brain diseases and cancer in humans and mice have been associated with spindle orientation defects. These defects are thought to lead to an im...

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Detalles Bibliográficos
Autores principales: Noatynska, Anna, Gotta, Monica, Meraldi, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529530/
https://www.ncbi.nlm.nih.gov/pubmed/23266953
http://dx.doi.org/10.1083/jcb.201209015

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