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Mitotic spindle (DIS)orientation and DISease: Cause or consequence?
Correct alignment of the mitotic spindle during cell division is crucial for cell fate determination, tissue organization, and development. Mutations causing brain diseases and cancer in humans and mice have been associated with spindle orientation defects. These defects are thought to lead to an im...
Autores principales: | Noatynska, Anna, Gotta, Monica, Meraldi, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529530/ https://www.ncbi.nlm.nih.gov/pubmed/23266953 http://dx.doi.org/10.1083/jcb.201209015 |
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