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Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota
Vaginal HIV microbicides offer great promise in preventing HIV transmission, but failures of phase 3 clinical trials, in which microbicide-treated subjects had an increased risk of HIV transmission, raised concerns about endpoints used to evaluate microbicide safety. A possible explanation for the i...
Autores principales: | Ravel, Jacques, Gajer, Pawel, Fu, Li, Mauck, Christine K., Koenig, Sara S. K., Sakamoto, Joyce, Motsinger-Reif, Alison A., Doncel, Gustavo F., Zeichner, Steven L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529542/ https://www.ncbi.nlm.nih.gov/pubmed/23249810 http://dx.doi.org/10.1128/mBio.00370-12 |
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