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TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients

AIM: To investigate the influence of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) subtypes in doctors’ decisions to use antihypertensive prescriptions at discharge for ischemic stroke patients in a real-world setting. METHODS: Using the China National Stroke Registry, we analyzed data fr...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Liu, Liping, Wang, Yilong, Zhao, Xingquan, Wang, Chunxue, Wang, Anxin, Wang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529652/
https://www.ncbi.nlm.nih.gov/pubmed/23269862
http://dx.doi.org/10.2147/PPA.S38565
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author Xu, Jie
Liu, Liping
Wang, Yilong
Zhao, Xingquan
Wang, Chunxue
Wang, Anxin
Wang, Yongjun
author_facet Xu, Jie
Liu, Liping
Wang, Yilong
Zhao, Xingquan
Wang, Chunxue
Wang, Anxin
Wang, Yongjun
author_sort Xu, Jie
collection PubMed
description AIM: To investigate the influence of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) subtypes in doctors’ decisions to use antihypertensive prescriptions at discharge for ischemic stroke patients in a real-world setting. METHODS: Using the China National Stroke Registry, we analyzed data from 12,063 hospitalized patients who had been diagnosed with ischemic stroke. The cause of ischemic stroke was classified according to the TOAST criteria. The information about the prescription of antihypertensive medication at discharge was extracted from medical records. Multivariate logistic regression was used to assess the impact of TOAST subtypes on the prescription of antihypertensive medication at discharge. RESULTS: Multivariate analysis showed that, compared with large artery atherosclerosis patients with moderate (<70%) stenosis, large artery atherosclerosis patients with severe (≥70%) stenosis or patients with stroke of undetermined etiology were less likely to be prescribed antihypertensive medication at discharge (odds ratio [OR], 0.72; 95% confidence interval [CI]: 0.59–0.88; OR, 0.71; 95% CI: 0.64–0.79), while patients with small artery occlusion were more likely to be prescribed antihypertensives (OR, 1.50; 95% CI: 1.33–1.69). CONCLUSION: The TOAST subtype is an important determinant of the prescription of antihypertensive medication for ischemic stroke patients at discharge in normal clinical practice.
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spelling pubmed-35296522012-12-26 TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients Xu, Jie Liu, Liping Wang, Yilong Zhao, Xingquan Wang, Chunxue Wang, Anxin Wang, Yongjun Patient Prefer Adherence Short Report AIM: To investigate the influence of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) subtypes in doctors’ decisions to use antihypertensive prescriptions at discharge for ischemic stroke patients in a real-world setting. METHODS: Using the China National Stroke Registry, we analyzed data from 12,063 hospitalized patients who had been diagnosed with ischemic stroke. The cause of ischemic stroke was classified according to the TOAST criteria. The information about the prescription of antihypertensive medication at discharge was extracted from medical records. Multivariate logistic regression was used to assess the impact of TOAST subtypes on the prescription of antihypertensive medication at discharge. RESULTS: Multivariate analysis showed that, compared with large artery atherosclerosis patients with moderate (<70%) stenosis, large artery atherosclerosis patients with severe (≥70%) stenosis or patients with stroke of undetermined etiology were less likely to be prescribed antihypertensive medication at discharge (odds ratio [OR], 0.72; 95% confidence interval [CI]: 0.59–0.88; OR, 0.71; 95% CI: 0.64–0.79), while patients with small artery occlusion were more likely to be prescribed antihypertensives (OR, 1.50; 95% CI: 1.33–1.69). CONCLUSION: The TOAST subtype is an important determinant of the prescription of antihypertensive medication for ischemic stroke patients at discharge in normal clinical practice. Dove Medical Press 2012-12-17 /pmc/articles/PMC3529652/ /pubmed/23269862 http://dx.doi.org/10.2147/PPA.S38565 Text en © 2012 Xu et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Short Report
Xu, Jie
Liu, Liping
Wang, Yilong
Zhao, Xingquan
Wang, Chunxue
Wang, Anxin
Wang, Yongjun
TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title_full TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title_fullStr TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title_full_unstemmed TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title_short TOAST subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
title_sort toast subtypes: its influence upon doctors’ decisions of antihypertensive prescription at discharge for ischemic stroke patients
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529652/
https://www.ncbi.nlm.nih.gov/pubmed/23269862
http://dx.doi.org/10.2147/PPA.S38565
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