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Use of Response Surface Methodology in the Formulation and Optimization of Bisoprolol Fumarate Matrix Tablets for Sustained Drug Release

The aim of this investigation was to develop and optimize bisoprolol fumarate matrix tablets for sustained release application by response surface methodology based on 2(3) factorial design. The effects of the amounts of calcium alginate, HPMC K4M, and Carbopol 943 in bisoprolol fumarate matrix tabl...

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Detalles Bibliográficos
Autores principales:	Malakar, Jadupati, Nayak, Amit Kumar, Goswami, Soumita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scholarly Research Network 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529867/ https://www.ncbi.nlm.nih.gov/pubmed/23378933 http://dx.doi.org/10.5402/2012/730624

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