Delayed-Type Hypersensitivity to Sand Fly Saliva in Humans from a Leishmaniasis-Endemic Area of Mali Is T(H)1-Mediated and Persists to Midlife

Immunity to sand fly saliva in rodents induces a T(H)1 delayed-type hypersensitivity (DTH) response conferring protection against leishmaniasis. The relevance of DTH to sand fly bites in humans living in a leishmaniasis-endemic area remains unknown. Here, we describe the duration and nature of DTH t...

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Detalles Bibliográficos
Autores principales: Oliveira, Fabiano, Traoré, Bourama, Gomes, Regis, Faye, Ousmane, Gilmore, Dana C, Keita, Somita, Traoré, Pierre, Teixeira, Clarissa, Coulibaly, Cheick A, Samake, Sibiry, Meneses, Claudio, Sissoko, Ibrahim, Fairhurst, Rick M, Fay, Michael P, Anderson, Jennifer M, Doumbia, Seydou, Kamhawi, Shaden, Valenzuela, Jesus G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529997/
https://www.ncbi.nlm.nih.gov/pubmed/22992802
http://dx.doi.org/10.1038/jid.2012.315

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