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Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death
Right atrial myxomas are rare primary tumors of the heart. They may remain asymptomatic or eventually cause constitutional signs and symptoms. Less frequently, obstruction of the tricuspid valve occurs, resulting in exertional dyspnea, syncope, or sudden death. Neurological manifestation as initial...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530247/ https://www.ncbi.nlm.nih.gov/pubmed/23271855 http://dx.doi.org/10.4103/0300-1652.103551 |
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author | Sabageh, Donatus Odujoko, Oluwole Olaniyi Komolafe, Akinwumi Oluwole |
author_facet | Sabageh, Donatus Odujoko, Oluwole Olaniyi Komolafe, Akinwumi Oluwole |
author_sort | Sabageh, Donatus |
collection | PubMed |
description | Right atrial myxomas are rare primary tumors of the heart. They may remain asymptomatic or eventually cause constitutional signs and symptoms. Less frequently, obstruction of the tricuspid valve occurs, resulting in exertional dyspnea, syncope, or sudden death. Neurological manifestation as initial presentation of atrial myxomas is rarely, if ever, associated with right atrial myxomas and may be secondary to cerebral infarction, cerebral hemorrhage and, more rarely subarachnoid hemorrhage. We review the case of a previously unknown, middle-aged Nigerian man who presented to hospital with severe headache and sudden loss of consciousness. A clinical diagnosis of hypertensive hemorrhagic cerebrovascular accident was made. The patient died suddenly a few hours after presentation. Post-mortem examination revealed a small intracerebral hemorrhage in the left superior temporal lobe as well as a large right atrial myxoma, a ventricular septal defect in the muscular septum, and right ventricular hypertrophy. The liver showed fatty change while the kidneys showed evidence of benign nephrosclerosis. Right atrial myxomas may, therefore, be remotely considered as a cause of intracranial hemorrhage, especially in the presence of predisposing cardiac anomalies such as a ventricular septal defect. Similarly, being a known cause of right heart failure, sudden death, and other constitutional derangements, it may contribute significantly to disease outcome. Hence, it should be given due consideration in the differential diagnosis of cerebrovascular accidents. |
format | Online Article Text |
id | pubmed-3530247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35302472012-12-27 Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death Sabageh, Donatus Odujoko, Oluwole Olaniyi Komolafe, Akinwumi Oluwole Niger Med J Case Report Right atrial myxomas are rare primary tumors of the heart. They may remain asymptomatic or eventually cause constitutional signs and symptoms. Less frequently, obstruction of the tricuspid valve occurs, resulting in exertional dyspnea, syncope, or sudden death. Neurological manifestation as initial presentation of atrial myxomas is rarely, if ever, associated with right atrial myxomas and may be secondary to cerebral infarction, cerebral hemorrhage and, more rarely subarachnoid hemorrhage. We review the case of a previously unknown, middle-aged Nigerian man who presented to hospital with severe headache and sudden loss of consciousness. A clinical diagnosis of hypertensive hemorrhagic cerebrovascular accident was made. The patient died suddenly a few hours after presentation. Post-mortem examination revealed a small intracerebral hemorrhage in the left superior temporal lobe as well as a large right atrial myxoma, a ventricular septal defect in the muscular septum, and right ventricular hypertrophy. The liver showed fatty change while the kidneys showed evidence of benign nephrosclerosis. Right atrial myxomas may, therefore, be remotely considered as a cause of intracranial hemorrhage, especially in the presence of predisposing cardiac anomalies such as a ventricular septal defect. Similarly, being a known cause of right heart failure, sudden death, and other constitutional derangements, it may contribute significantly to disease outcome. Hence, it should be given due consideration in the differential diagnosis of cerebrovascular accidents. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3530247/ /pubmed/23271855 http://dx.doi.org/10.4103/0300-1652.103551 Text en Copyright: © Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sabageh, Donatus Odujoko, Oluwole Olaniyi Komolafe, Akinwumi Oluwole Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title | Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title_full | Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title_fullStr | Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title_full_unstemmed | Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title_short | Right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
title_sort | right atrial myxoma as a possible cause of hemorrhagic stroke and sudden death |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530247/ https://www.ncbi.nlm.nih.gov/pubmed/23271855 http://dx.doi.org/10.4103/0300-1652.103551 |
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