Pharmaceutical standardization of Samaguna Bali Jarita Rasasindura prepared by conventional and modified method

INTRODUCTION: Rasasindura (RS) is one of the unique mercurial preparations commonly used in Ayurveda therapeutics. The traditional procedure followed for preparing RS in the classical furnace has several drawbacks, such as difficulty in controlling temperature, consumption of large quantity of fuel, and excess human effort. AIMS & OBJECTIVE: The present study was conducted to evaluate an alternate method to prepare RS by using an electrical muffle furnace (EMF) and to standardize this method. MATERIALS AND METHODS: RS was prepared by adapting similar temperature pattern in both the traditional and EMF methods, and observations were recorded. Obtained product was subjected to orgennoleptic and physico-chemical analysis. RESULT: No remarkable differences were seen in observations of both preparations, except the melting of Kajjali, appearance of flame, and appearance of desired characteristics of product formation, which were observed at 190, 496, and 567°C in the traditional method and at 180, 473, and 560°C in EMF, respectively. Yield of the traditional method was 53.5% whereas in EMF, it was 50.83%. Organoleptic and physicochemical analysis revealed no significant deviation in values. CONCLUSION: The present study reveals that the traditional method of preparing RS can be effectively replaced by the EMF with some added advantages.