Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

BACKGROUND: Inhibitors targeting the cell cycle-regulated aurora kinase A (AURKA) are currently being developed. Here, we examine the prognostic impact of AURKA in node-negative breast cancer patients without adjuvant systemic therapy (n = 766). METHODS: AURKA was analyzed using microarray-based gen...

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Detalles Bibliográficos
Autores principales: Siggelkow, Wulf, Boehm, Daniel, Gebhard, Susanne, Battista, Marco, Sicking, Isabel, Lebrecht, Antje, Solbach, Christine, Hellwig, Birte, Rahnenführer, Jörg, Koelbl, Heinz, Gehrmann, Mathias, Marchan, Rosemarie, Cadenas, Cristina, Hengstler, Jan G, Schmidt, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530429/
https://www.ncbi.nlm.nih.gov/pubmed/23186136
http://dx.doi.org/10.1186/1471-2407-12-562

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