Production of Functional Soluble Dectin-1 Glycoprotein Using an IRES-Linked Destabilized-Dihydrofolate Reductase Expression Vector

Dectin-1 (CLEC7A) is a C-type lectin receptor that binds to β-glucans found in fungal cell walls to act as a major pattern recognition receptor (PRR). Since β-glucans epitope is not present in human cells, we are of the opinion that Dectin-1 can have therapeutic functions against fungal infections....

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Detalles Bibliográficos
Autores principales: Ng, Say Kong, Tan, Tessa Rui Min, Wang, Yang, Ng, Daniel, Goh, Lin-Tang, Bardor, Muriel, Wong, Victor Vai Tak, Lam, Kong Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530475/
https://www.ncbi.nlm.nih.gov/pubmed/23300776
http://dx.doi.org/10.1371/journal.pone.0052785

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