Cargando…
Cataracts and Microphthalmia Caused by a Gja8 Mutation in Extracellular Loop 2
The mouse semi-dominant Nm2249 mutation displays variable cataracts in heterozygous mice and smaller lenses with severe cataracts in homozygous mice. This mutation is caused by a Gja8(R205G) point mutation in the second extracellular loop of the Cx50 (or α8 connexin) protein. Immunohistological data...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530494/ https://www.ncbi.nlm.nih.gov/pubmed/23300808 http://dx.doi.org/10.1371/journal.pone.0052894 |