Tissue Factor Pathway Inhibitor 2 Is Found in Skin and Its C-Terminal Region Encodes for Antibacterial Activity

BACKGROUND: Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding. METHODOLOGY AND PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Papareddy, Praveen, Kalle, Martina, Sørensen, Ole E., Lundqvist, Katarina, Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530512/
https://www.ncbi.nlm.nih.gov/pubmed/23300768
http://dx.doi.org/10.1371/journal.pone.0052772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530512/
https://www.ncbi.nlm.nih.gov/pubmed/23300768
http://dx.doi.org/10.1371/journal.pone.0052772

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