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Tissue Factor Pathway Inhibitor 2 Is Found in Skin and Its C-Terminal Region Encodes for Antibacterial Activity
BACKGROUND: Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding. METHODOLOGY AND PRINCIPAL FINDI...
Autores principales: | Papareddy, Praveen, Kalle, Martina, Sørensen, Ole E., Lundqvist, Katarina, Mörgelin, Matthias, Malmsten, Martin, Schmidtchen, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530512/ https://www.ncbi.nlm.nih.gov/pubmed/23300768 http://dx.doi.org/10.1371/journal.pone.0052772 |
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