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The RenTg Mice: A Powerful Tool to Study Renin-Dependent Chronic Kidney Disease
BACKGROUND: Several studies have shown that activation of the renin-angiotensin system may lead to hypertension, a major risk factor for the development of chronic kidney disease (CKD). The existing hypertension-induced CDK mouse models are quite fast and consequently away from the human pathology....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530557/ https://www.ncbi.nlm.nih.gov/pubmed/23300650 http://dx.doi.org/10.1371/journal.pone.0052362 |