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Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates

Transfusions are a cause of significant patient morbidity as well as expense. Anesthesia literature has examined controlled intraoperative hypotension as a means for reducing blood loss and transfusions. Our hypothesis is that inversely increased blood pressure post-operatively would then lead to in...

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Autores principales: Russo, Russell R., Dasa, Vinod, Duarte, Robert, Beakley, Burton, Mishra, Manish, Thompson, Hilary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530586/
https://www.ncbi.nlm.nih.gov/pubmed/23300531
http://dx.doi.org/10.1371/journal.pone.0050967
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author Russo, Russell R.
Dasa, Vinod
Duarte, Robert
Beakley, Burton
Mishra, Manish
Thompson, Hilary
author_facet Russo, Russell R.
Dasa, Vinod
Duarte, Robert
Beakley, Burton
Mishra, Manish
Thompson, Hilary
author_sort Russo, Russell R.
collection PubMed
description Transfusions are a cause of significant patient morbidity as well as expense. Anesthesia literature has examined controlled intraoperative hypotension as a means for reducing blood loss and transfusions. Our hypothesis is that inversely increased blood pressure post-operatively would then lead to increased blood loss and transfusions. We examined 105 consecutive patients who underwent TKA. We found a significant odds ratio of 1.123 for pre-operative hematocrit. For post-operative blood pressure, we calculated an insignificant odds ratio of 1.007, proving no relationship between post-operative blood pressure and transfusions. This is the first study to examine increased post-operative blood pressure's contribution to transfusion rates. Although we confirmed that low pre-operative hematocrit contributes to increased transfusions, we did not find a relationship between post-operative blood pressure and transfusions.
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spelling pubmed-35305862013-01-08 Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates Russo, Russell R. Dasa, Vinod Duarte, Robert Beakley, Burton Mishra, Manish Thompson, Hilary PLoS One Research Article Transfusions are a cause of significant patient morbidity as well as expense. Anesthesia literature has examined controlled intraoperative hypotension as a means for reducing blood loss and transfusions. Our hypothesis is that inversely increased blood pressure post-operatively would then lead to increased blood loss and transfusions. We examined 105 consecutive patients who underwent TKA. We found a significant odds ratio of 1.123 for pre-operative hematocrit. For post-operative blood pressure, we calculated an insignificant odds ratio of 1.007, proving no relationship between post-operative blood pressure and transfusions. This is the first study to examine increased post-operative blood pressure's contribution to transfusion rates. Although we confirmed that low pre-operative hematocrit contributes to increased transfusions, we did not find a relationship between post-operative blood pressure and transfusions. Public Library of Science 2012-12-26 /pmc/articles/PMC3530586/ /pubmed/23300531 http://dx.doi.org/10.1371/journal.pone.0050967 Text en © 2012 Russo et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Russo, Russell R.
Dasa, Vinod
Duarte, Robert
Beakley, Burton
Mishra, Manish
Thompson, Hilary
Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title_full Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title_fullStr Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title_full_unstemmed Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title_short Post-Operative Hypertension after Total Knee Arthroplasty and the Effects on Transfusion Rates
title_sort post-operative hypertension after total knee arthroplasty and the effects on transfusion rates
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530586/
https://www.ncbi.nlm.nih.gov/pubmed/23300531
http://dx.doi.org/10.1371/journal.pone.0050967
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