Major Chromosomal Breakpoint Intervals in Breast Cancer Co-Localize with Differentially Methylated Regions

Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique...

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Detalles Bibliográficos
Autores principales: Eric Tang, Man-Hung, Varadan, Vinay, Kamalakaran, Sitharthan, Zhang, Michael Q., Dimitrova, Nevenka, Hicks, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530719/
https://www.ncbi.nlm.nih.gov/pubmed/23293768
http://dx.doi.org/10.3389/fonc.2012.00197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530719/
https://www.ncbi.nlm.nih.gov/pubmed/23293768
http://dx.doi.org/10.3389/fonc.2012.00197

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