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Major Chromosomal Breakpoint Intervals in Breast Cancer Co-Localize with Differentially Methylated Regions
Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique...
Autores principales: | Eric Tang, Man-Hung, Varadan, Vinay, Kamalakaran, Sitharthan, Zhang, Michael Q., Dimitrova, Nevenka, Hicks, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530719/ https://www.ncbi.nlm.nih.gov/pubmed/23293768 http://dx.doi.org/10.3389/fonc.2012.00197 |
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