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The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation
The exon-junction complex (EJC) deposited on a newly spliced mRNA plays an important role in subsequent mRNA metabolic events. Here we show that an EJC core heterodimer, Y14/Magoh, specifically associates with mRNA-degradation factors, including the mRNA-decapping complex and exoribonucleases, where...
Autores principales: | Chuang, Tzu-Wei, Chang, Wei-Lun, Lee, Kuo-Ming, Tarn, Woan-Yuh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530774/ https://www.ncbi.nlm.nih.gov/pubmed/23115303 http://dx.doi.org/10.1091/mbc.E12-03-0217 |
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