Rfam 11.0: 10 years of RNA families

The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is r...

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Autores principales: Burge, Sarah W., Daub, Jennifer, Eberhardt, Ruth, Tate, John, Barquist, Lars, Nawrocki, Eric P., Eddy, Sean R., Gardner, Paul P., Bateman, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531072/
https://www.ncbi.nlm.nih.gov/pubmed/23125362
http://dx.doi.org/10.1093/nar/gks1005
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author Burge, Sarah W.
Daub, Jennifer
Eberhardt, Ruth
Tate, John
Barquist, Lars
Nawrocki, Eric P.
Eddy, Sean R.
Gardner, Paul P.
Bateman, Alex
author_facet Burge, Sarah W.
Daub, Jennifer
Eberhardt, Ruth
Tate, John
Barquist, Lars
Nawrocki, Eric P.
Eddy, Sean R.
Gardner, Paul P.
Bateman, Alex
author_sort Burge, Sarah W.
collection PubMed
description The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.
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spelling pubmed-35310722013-03-07 Rfam 11.0: 10 years of RNA families Burge, Sarah W. Daub, Jennifer Eberhardt, Ruth Tate, John Barquist, Lars Nawrocki, Eric P. Eddy, Sean R. Gardner, Paul P. Bateman, Alex Nucleic Acids Res Articles The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license. Oxford University Press 2013-01 2012-11-02 /pmc/articles/PMC3531072/ /pubmed/23125362 http://dx.doi.org/10.1093/nar/gks1005 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Articles
Burge, Sarah W.
Daub, Jennifer
Eberhardt, Ruth
Tate, John
Barquist, Lars
Nawrocki, Eric P.
Eddy, Sean R.
Gardner, Paul P.
Bateman, Alex
Rfam 11.0: 10 years of RNA families
title Rfam 11.0: 10 years of RNA families
title_full Rfam 11.0: 10 years of RNA families
title_fullStr Rfam 11.0: 10 years of RNA families
title_full_unstemmed Rfam 11.0: 10 years of RNA families
title_short Rfam 11.0: 10 years of RNA families
title_sort rfam 11.0: 10 years of rna families
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531072/
https://www.ncbi.nlm.nih.gov/pubmed/23125362
http://dx.doi.org/10.1093/nar/gks1005
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