Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides

Quorum-sensing (QS) peptides are biologically attractive molecules, with a wide diversity of structures and prone to modifications altering or presenting new functionalities. Therefore, the Quorumpeps database (http://quorumpeps.ugent.be) is developed to give a structured overview of the QS oligopep...

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Autores principales: Wynendaele, Evelien, Bronselaer, Antoon, Nielandt, Joachim, D’Hondt, Matthias, Stalmans, Sofie, Bracke, Nathalie, Verbeke, Frederick, Van De Wiele, Christophe, De Tré, Guy, De Spiegeleer, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531179/
https://www.ncbi.nlm.nih.gov/pubmed/23180797
http://dx.doi.org/10.1093/nar/gks1137
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author Wynendaele, Evelien
Bronselaer, Antoon
Nielandt, Joachim
D’Hondt, Matthias
Stalmans, Sofie
Bracke, Nathalie
Verbeke, Frederick
Van De Wiele, Christophe
De Tré, Guy
De Spiegeleer, Bart
author_facet Wynendaele, Evelien
Bronselaer, Antoon
Nielandt, Joachim
D’Hondt, Matthias
Stalmans, Sofie
Bracke, Nathalie
Verbeke, Frederick
Van De Wiele, Christophe
De Tré, Guy
De Spiegeleer, Bart
author_sort Wynendaele, Evelien
collection PubMed
description Quorum-sensing (QS) peptides are biologically attractive molecules, with a wide diversity of structures and prone to modifications altering or presenting new functionalities. Therefore, the Quorumpeps database (http://quorumpeps.ugent.be) is developed to give a structured overview of the QS oligopeptides, describing their microbial origin (species), functionality (method, result and receptor), peptide links and chemical characteristics (3D-structure-derived physicochemical properties). The chemical diversity observed within this group of QS signalling molecules can be used to develop new synthetic bio-active compounds.
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spelling pubmed-35311792013-01-03 Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides Wynendaele, Evelien Bronselaer, Antoon Nielandt, Joachim D’Hondt, Matthias Stalmans, Sofie Bracke, Nathalie Verbeke, Frederick Van De Wiele, Christophe De Tré, Guy De Spiegeleer, Bart Nucleic Acids Res Articles Quorum-sensing (QS) peptides are biologically attractive molecules, with a wide diversity of structures and prone to modifications altering or presenting new functionalities. Therefore, the Quorumpeps database (http://quorumpeps.ugent.be) is developed to give a structured overview of the QS oligopeptides, describing their microbial origin (species), functionality (method, result and receptor), peptide links and chemical characteristics (3D-structure-derived physicochemical properties). The chemical diversity observed within this group of QS signalling molecules can be used to develop new synthetic bio-active compounds. Oxford University Press 2013-01 2012-11-23 /pmc/articles/PMC3531179/ /pubmed/23180797 http://dx.doi.org/10.1093/nar/gks1137 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Articles
Wynendaele, Evelien
Bronselaer, Antoon
Nielandt, Joachim
D’Hondt, Matthias
Stalmans, Sofie
Bracke, Nathalie
Verbeke, Frederick
Van De Wiele, Christophe
De Tré, Guy
De Spiegeleer, Bart
Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title_full Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title_fullStr Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title_full_unstemmed Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title_short Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
title_sort quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531179/
https://www.ncbi.nlm.nih.gov/pubmed/23180797
http://dx.doi.org/10.1093/nar/gks1137
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