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High-resolution deep sequencing reveals biodiversity, population structure, and persistence of HIV-1 quasispecies within host ecosystems

BACKGROUND: Deep sequencing provides the basis for analysis of biodiversity of taxonomically similar organisms in an environment. While extensively applied to microbiome studies, population genetics studies of viruses are limited. To define the scope of HIV-1 population biodiversity within infected...

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Detalles Bibliográficos
Autores principales: Yin, Li, Liu, Li, Sun, Yijun, Hou, Wei, Lowe, Amanda C, Gardner, Brent P, Salemi, Marco, Williams, Wilton B, Farmerie, William G, Sleasman, John W, Goodenow, Maureen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531307/
https://www.ncbi.nlm.nih.gov/pubmed/23244298
http://dx.doi.org/10.1186/1742-4690-9-108