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Targeted Delivery of GDNF through the Blood–Brain Barrier by MRI-Guided Focused Ultrasound

Neurotrophic factors, such as glial cell line-derived neurotrophic factor (GDNF), are promising therapeutic agents for neurodegenerative diseases. However, the application of GDNF to treat these diseases effectively is limited because the blood–brain barrier (BBB) prevents the local delivery of macr...

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Detalles Bibliográficos
Autores principales:	Wang, Feng, Shi, Yu, Lu, Lin, Liu, Li, Cai, Youli, Zheng, Hairong, Liu, Xin, Yan, Fei, Zou, Chao, Sun, Chengyu, Shi, Jie, Lu, Shukun, Chen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531370/ https://www.ncbi.nlm.nih.gov/pubmed/23300823 http://dx.doi.org/10.1371/journal.pone.0052925

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