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Cytoplasmic Skp2 Expression Is Associated with p-Akt1 and Predicts Poor Prognosis in Human Breast Carcinomas

BACKGROUND: S-phase kinase protein 2 (Skp2), an oncogenic protein, is a key regulator in different cellular and molecular processes, through ubiquitin-proteasome degradation pathway. Increased levels of Skp2 are observed in various types of cancer and associated with poor prognosis. However, in huma...

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Wei, Xiao-Long, Huang, Wen-He, Chen, Chun-Fa, Bai, Jing-Wen, Zhang, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531378/ https://www.ncbi.nlm.nih.gov/pubmed/23300741 http://dx.doi.org/10.1371/journal.pone.0052675

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