The Apoptotic Effects of Toosendanin Are Partially Mediated by Activation of Deoxycytidine Kinase in HL-60 Cells

Triterpenoid toosendanin (TSN) exhibits potent cytotoxic activity through inducing apoptosis in a variety of cancer cell lines. However, the target and mechanism of the apoptotic effects by TSN remain unknown. In this study, we captured a specific binding protein of TSN in HL-60 cells by serial affi...

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Detalles Bibliográficos
Autores principales: Ju, Jianming, Qi, Zhichao, Cai, Xueting, Cao, Peng, Huang, Yan, Wang, Shuzhen, Liu, Nan, Chen, Yijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531419/
https://www.ncbi.nlm.nih.gov/pubmed/23300702
http://dx.doi.org/10.1371/journal.pone.0052536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531419/
https://www.ncbi.nlm.nih.gov/pubmed/23300702
http://dx.doi.org/10.1371/journal.pone.0052536

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