Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is the first member in a new family of protein-lipid complexes with broad tumoricidal activity. Elucidating the molecular structure and the domains crucial for HAMLET formation is fundamental for understanding its tumoricidal function. Here...

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Detalles Bibliográficos
Autores principales: Ho CS, James, Rydstrom, Anna, Manimekalai, Malathy Sony Subramanian, Svanborg, Catharina, Grüber, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531425/
https://www.ncbi.nlm.nih.gov/pubmed/23300861
http://dx.doi.org/10.1371/journal.pone.0053051

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