Activation of Hydrogen Peroxide to Peroxytetradecanoic Acid Is Responsible for Potent Inhibition of Protein Tyrosine Phosphatase CD45

Hydrogen peroxide induces oxidation and consequently inactivation of many protein tyrosine phosphatases. It was found that hydrogen peroxide, in the presence of carboxylic acids, was efficiently activated to form even more potent oxidant - peroxy acid. We have found that peroxytetradecanoic acid dec...

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Detalles Bibliográficos
Autores principales: Kuban-Jankowska, Alicja, Tuszynski, Jack A., Winter, Philip, Gorska, Magdalena, Knap, Narcyz, Wozniak, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531430/
https://www.ncbi.nlm.nih.gov/pubmed/23300686
http://dx.doi.org/10.1371/journal.pone.0052495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531430/
https://www.ncbi.nlm.nih.gov/pubmed/23300686
http://dx.doi.org/10.1371/journal.pone.0052495

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