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Activation of Hydrogen Peroxide to Peroxytetradecanoic Acid Is Responsible for Potent Inhibition of Protein Tyrosine Phosphatase CD45
Hydrogen peroxide induces oxidation and consequently inactivation of many protein tyrosine phosphatases. It was found that hydrogen peroxide, in the presence of carboxylic acids, was efficiently activated to form even more potent oxidant - peroxy acid. We have found that peroxytetradecanoic acid dec...
Autores principales: | Kuban-Jankowska, Alicja, Tuszynski, Jack A., Winter, Philip, Gorska, Magdalena, Knap, Narcyz, Wozniak, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531430/ https://www.ncbi.nlm.nih.gov/pubmed/23300686 http://dx.doi.org/10.1371/journal.pone.0052495 |
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