Diesterified Nitrone Rescues Nitroso-Redox Levels and Increases Myocyte Contraction Via Increased SR Ca(2+) Handling

Nitric oxide (NO) and superoxide (O(2) (−)) are important cardiac signaling molecules that regulate myocyte contraction. For appropriate regulation, NO and O(2) (.−) must exist at defined levels. Unfortunately, the NO and O(2) (.−) levels are altered in many cardiomyopathies (heart failure, ischemia...

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Detalles Bibliográficos
Autores principales: Traynham, Christopher J., Roof, Steve R., Wang, Honglan, Prosak, Robert A., Tang, Lifei, Viatchenko-Karpinski, Serge, Ho, Hsiang-Ting, Racoma, Ira O., Catalano, Dominic J., Huang, Xin, Han, Yongbin, Kim, Shang-U, Gyorke, Sandor, Billman, George E., Villamena, Frederick A., Ziolo, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531448/
https://www.ncbi.nlm.nih.gov/pubmed/23300588
http://dx.doi.org/10.1371/journal.pone.0052005

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