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Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening
Nuclear entry and exit of the NF-κB family of dimeric transcription factors plays an essential role in regulating cellular responses to inflammatory stress. The dynamics of this nuclear translocation can vary significantly within a cell population and may dramatically change e.g. upon drug exposure....
Autores principales: | Di, Zi, Herpers, Bram, Fredriksson, Lisa, Yan, Kuan, van de Water, Bob, Verbeek, Fons J., Meerman, John H. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531459/ https://www.ncbi.nlm.nih.gov/pubmed/23300644 http://dx.doi.org/10.1371/journal.pone.0052337 |
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