Cargando…
Approaching the Functional Annotation of Fungal Virulence Factors Using Cross-Species Genetic Interaction Profiling
In many human fungal pathogens, genes required for disease remain largely unannotated, limiting the impact of virulence gene discovery efforts. We tested the utility of a cross-species genetic interaction profiling approach to obtain clues to the molecular function of unannotated pathogenicity facto...
Autores principales: | Brown, Jessica C. S., Madhani, Hiten D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531484/ https://www.ncbi.nlm.nih.gov/pubmed/23300468 http://dx.doi.org/10.1371/journal.pgen.1003168 |
Ejemplares similares
-
A Link between Virulence and Homeostatic Responses to Hypoxia during Infection by the Human Fungal Pathogen Cryptococcus neoformans
por: Chun, Cheryl D, et al.
Publicado: (2007) -
Ctr2 Links Copper Homeostasis to Polysaccharide Capsule Formation and Phagocytosis Inhibition in the Human Fungal Pathogen Cryptococcus neoformans
por: Chun, Cheryl D., et al.
Publicado: (2010) -
Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence
por: Clarke, Starlynn C., et al.
Publicado: (2016) -
Quorum Sensing in Fungi: Q&A
por: Madhani, Hiten D.
Publicado: (2011) -
Coordinate control of gene expression noise and interchromosomal interactions in a MAPK pathway
por: McCullagh, Emma, et al.
Publicado: (2010)