Cargando…
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
Mosaic Variegated Aneuploidy (MVA) syndrome is a rare autosomal recessive disorder characterized by inaccurate chromosome segregation and high rates of near-diploid aneuploidy. Children with MVA syndrome die at an early age, are cancer prone, and have progeroid features like facial dysmorphisms, sho...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531486/ https://www.ncbi.nlm.nih.gov/pubmed/23300461 http://dx.doi.org/10.1371/journal.pgen.1003138 |