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Hsp90 Orchestrates Transcriptional Regulation by Hsf1 and Cell Wall Remodelling by MAPK Signalling during Thermal Adaptation in a Pathogenic Yeast

Thermal adaptation is essential in all organisms. In yeasts, the heat shock response is commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased genetic screens with directed molecular dissection to demonstrate that multiple signalling cascades contribute to thermal ad...

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Detalles Bibliográficos
Autores principales: Leach, Michelle D., Budge, Susan, Walker, Louise, Munro, Carol, Cowen, Leah E., Brown, Alistair J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531498/
https://www.ncbi.nlm.nih.gov/pubmed/23300438
http://dx.doi.org/10.1371/journal.ppat.1003069