Cargando…

Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

Inflammasomes sense infection and cellular damage and are critical for triggering inflammation through IL-1β production. In carcinogenesis, inflammasomes may have contradictory roles through facilitating antitumour immunity and inducing oncogenic factors. Their function in cancer remains poorly char...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Lih-Chyang, Wang, Li-Jie, Tsang, Nang-Ming, Ojcius, David M, Chen, Chia-Chun, OuYang, Chun-Nan, Hsueh, Chuen, Liang, Ying, Chang, Kai-Ping, Chen, Chiu-Chin, Chang, Yu-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531603/ https://www.ncbi.nlm.nih.gov/pubmed/23065753 http://dx.doi.org/10.1002/emmm.201201569

Ejemplares similares

Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis
por: Chung, I-Che, et al.
Publicado: (2016)

Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation
por: Chung, I-Che, et al.
Publicado: (2018)

Matrix metalloproteinase 12 is induced by heterogeneous nuclear ribonucleoprotein K and promotes migration and invasion in nasopharyngeal carcinoma
por: Chung, I-Che, et al.
Publicado: (2014)

Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice
por: Chung, I-Che, et al.
Publicado: (2019)

Targeted sequencing of cancer‐related genes in nasopharyngeal carcinoma identifies mutations in the TGF‐β pathway
por: Chung, An‐Ko, et al.
Publicado: (2019)

Perspective: Contribution of Epstein–Barr virus (EBV) Reactivation to the Carcinogenicity of Nasopharyngeal Cancer Cells
por: Wu, Chung-Chun, et al.
Publicado: (2018)

ASC contributes to metastasis of oral cavity squamous cell carcinoma
por: Wu, Chi-Sheng, et al.
Publicado: (2016)

BAFF-driven NLRP3 inflammasome activation in B cells
por: Lim, Ken-Hong, et al.
Publicado: (2020)

Immunotherapeutic approaches in EBV-associated nasopharyngeal carcinoma
por: Li, Wenting, et al.
Publicado: (2023)

Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition
por: Lin, Hsin-Chung, et al.
Publicado: (2020)

Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation
por: Lin, Hsin-Chung, et al.
Publicado: (2021)

Pathogenesis and Diagnostic Significance of EBV-miR-BARTs in Nasopharyngeal Carcinoma
por: Wu, Zhen, et al.
Publicado: (2022)

The diagnostic value of EBV-DNA and EBV-related antibodies detection for nasopharyngeal carcinoma: a meta-analysis
por: Liu, Weixing, et al.
Publicado: (2021)

MET is required for the recruitment of anti-tumoural neutrophils
por: Finisguerra, Veronica, et al.
Publicado: (2015)

Efficient Immortalization of Primary Nasopharyngeal Epithelial Cells for EBV Infection Study
por: Yip, Yim Ling, et al.
Publicado: (2013)

Multimodality Management of EBV-Associated Nasopharyngeal Carcinoma
por: Yu, Justin, et al.
Publicado: (2021)

Monoamine oxidase A is down-regulated in EBV-associated nasopharyngeal carcinoma
por: Lee, Hui Min, et al.
Publicado: (2020)

Systematic comparison of plasma EBV DNA, anti‐EBV antibodies and miRNA levels for early detection and prognosis of nasopharyngeal carcinoma
por: Tan, Lu Ping, et al.
Publicado: (2019)

A 3-gene signature comprising CDH4, STAT4 and EBV-encoded LMP1 for early diagnosis and predicting disease progression of nasopharyngeal carcinoma
por: Liu, Shu-Chen, et al.
Publicado: (2023)

Nasopharyngeal carcinoma: an EBV-associated tumour not significantly influenced by HIV-induced immunosuppression. The AIDS/Cancer Working Group.
por: Melbye, M., et al.
Publicado: (1996)

EBV based cancer prevention and therapy in nasopharyngeal carcinoma
por: Cao, Ya
Publicado: (2017)

Updates on Epstein–Barr Virus (EBV)-Associated Nasopharyngeal Carcinoma: Emphasis on the Latent Gene Products of EBV
por: Ahmed, Naveed, et al.
Publicado: (2022)

Performance of Plasma HSP90α, Serum EBV VCA IgA Antibody and Plasma EBV DNA for the Diagnosis and Prognosis Prediction of Nasopharyngeal Carcinoma
por: Ye, Qian, et al.
Publicado: (2021)

Prognostication of serial post-intensity-modulated radiation therapy undetectable plasma EBV DNA for nasopharyngeal carcinoma
por: Lee, Victor Ho-Fun, et al.
Publicado: (2016)

Emodin ameliorates acute pancreatitis-induced lung injury by suppressing NLRP3 inflammasome-mediated neutrophil recruitment
por: Jiang, Nan, et al.
Publicado: (2021)

CD44+ Cancer Stem-Like Cells in EBV-Associated Nasopharyngeal Carcinoma
por: Lun, Samantha Wei-Man, et al.
Publicado: (2012)

Increased risk of incident nasopharyngeal carcinoma with exposure to air pollution
por: Fan, Hueng-Chuen, et al.
Publicado: (2018)

EBV-encoded RNA via TLR3 induces inflammation in nasopharyngeal carcinoma
por: Li, Zhi, et al.
Publicado: (2015)

Effects of oral maintenance chemotherapy and predictive value of circulating EBV DNA in metastatic nasopharyngeal carcinoma
por: Zhou, Han, et al.
Publicado: (2020)

Emodin Inhibits EBV Reactivation and Represses NPC Tumorigenesis
por: Wu, Chung-Chun, et al.
Publicado: (2019)

A Review on the Application of PD-1 Blockade in EBV-Associated Nasopharyngeal Carcinoma Immunotherapy
por: Bian, Jin, et al.
Publicado: (2022)

Intralesional EBV-DNA load as marker of prognosis for nasopharyngeal cancer
por: Nilsson, Johan S., et al.
Publicado: (2019)

EBV Infection and Its Regulated Metabolic Reprogramming in Nasopharyngeal Tumorigenesis
por: Yang, Tingting, et al.
Publicado: (2022)

Differential expression of EBV proteins LMP1 and BHFR1 in EBV-associated gastric and nasopharyngeal cancer tissues
por: WANG, AILIANG, et al.
Publicado: (2016)

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells
por: Zhang, Guitao, et al.
Publicado: (2013)

Roles of Inflammasomes in Epstein–Barr Virus-Associated Nasopharyngeal Cancer
por: Looi, Chin King, et al.
Publicado: (2021)

Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy
por: Li, Jiang, et al.
Publicado: (2007)

Positive regulation of TAZ expression by EBV-LMP1 contributes to cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma
por: He, Jiang, et al.
Publicado: (2016)

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
por: Lin, Weitao, et al.
Publicado: (2018)

Novel EBV LMP-2-affibody and affitoxin in molecular imaging and targeted therapy of nasopharyngeal carcinoma
por: Zhu, Shanli, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hmgntn7q1s48ue4jproulfupt0