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WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis
Elevated levels of nuclear β-catenin are associated with higher rates of survival in patients with melanoma, raising questions as to how ß-catenin is regulated in this context. In the present study, we investigated the formal possibility that the secretion of WNT ligands that stabilize ß-catenin may...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
WILEY-VCH Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531604/ https://www.ncbi.nlm.nih.gov/pubmed/23129487 http://dx.doi.org/10.1002/emmm.201201486 |