Cargando…

MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury

Intestinal ischemia/reperfusion (I/R) injury causes inflammation and tissue damage and is associated with high morbidity and mortality. Uncontrolled activation of the innate immune system through toll-like receptors (Tlr) plays a key role in I/R-mediated tissue damage but the underlying mechanisms h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chassin, Cécilia, Hempel, Cordelia, Stockinger, Silvia, Dupont, Aline, Kübler, Joachim F, Wedemeyer, Jochen, Vandewalle, Alain, Hornef, Mathias W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531605/ https://www.ncbi.nlm.nih.gov/pubmed/23143987 http://dx.doi.org/10.1002/emmm.201201298

Ejemplares similares

miR-146a Ameliorates Liver Ischemia/Reperfusion Injury by Suppressing IRAK1 and TRAF6
por: Jiang, Weiwei, et al.
Publicado: (2014)

Correction: miR-146a Ameliorates Liver Ischemia/Reperfusion Injury by Suppressing IRAK1 and TRAF6
por: Jiang, Weiwei, et al.
Publicado: (2023)

Potentiation of Epithelial Innate Host Responses by Intercellular Communication
por: Dolowschiak, Tamas, et al.
Publicado: (2010)

Hormonal control of the renal immune response and antibacterial host defense by arginine vasopressin
por: Chassin, Cécilia, et al.
Publicado: (2007)

Human urine-derived stem cells protect against renal ischemia/reperfusion injury in a rat model via exosomal miR-146a-5p which targets IRAK1
por: Li, Xirui, et al.
Publicado: (2020)

Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions
por: Vandewalle, Alain, et al.
Publicado: (2014)

Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells
por: Hornef, Mathias W., et al.
Publicado: (2003)

MicroRNA-146a Contributes to SCI Recovery via Regulating TRAF6 and IRAK1 Expression
por: Wei, Jinsong, et al.
Publicado: (2016)

Toll-like Receptor 4 Resides in the Golgi Apparatus and Colocalizes with Internalized Lipopolysaccharide in Intestinal Epithelial Cells
por: Hornef, Mathias W., et al.
Publicado: (2002)

O-Antigen Delays Lipopolysaccharide Recognition and Impairs Antibacterial Host Defense in Murine Intestinal Epithelial Cells
por: Duerr, Claudia U., et al.
Publicado: (2009)

Irak : cinco años después /
por: Rosas, María Cristina
Publicado: (2008)

miR-146a Enhances the Oncogenicity of Oral Carcinoma by Concomitant Targeting of the IRAK1, TRAF6 and NUMB Genes
por: Hung, Pei-Shi, et al.
Publicado: (2013)

miR-146a-5p promotes replication of infectious bronchitis virus by targeting IRAK2 and TNFRSF18
por: Liu, Hui, et al.
Publicado: (2018)

MicroRNA-146a overexpression alleviates intestinal ischemia/reperfusion-induced acute lung injury in mice
por: Li, Gehui, et al.
Publicado: (2021)

IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies
por: Bennett, Joshua, et al.
Publicado: (2022)

Association of microRNA-146a and their target gene IRAK-1 polymorphism with enthesitis related arthritis category of juvenile idiopathic arthritis
por: Singh, Sushma, et al.
Publicado: (2014)

miR‑146a‑5p negatively regulates the IL‑1β‑stimulated inflammatory response via downregulation of the IRAK1/TRAF6 signaling pathway in human intestinal epithelial cells
por: Li, Yanli, et al.
Publicado: (2022)

IRAK1 mediates TLR4-induced ABCA1 downregulation and lipid accumulation in VSMCs
por: Guo, L, et al.
Publicado: (2015)

Outgrowing IRAK-4
por: Bashyam, Hema
Publicado: (2007)

IRAK signalling in cancer
por: Rhyasen, G W, et al.
Publicado: (2015)

IRAK2 Downregulation in Triple-Negative Breast Cancer Cells Decreases Cellular Growth In Vitro and Delays Tumour Progression in Murine Models
por: Ferraro, Francesca, et al.
Publicado: (2023)

MicroRNA-146a Represses Mycobacteria-Induced Inflammatory Response and Facilitates Bacterial Replication via Targeting IRAK-1 and TRAF-6
por: Li, Shuo, et al.
Publicado: (2013)

miR-146a is essential for lipopolysaccharide (LPS)-induced cross-tolerance against kidney ischemia/reperfusion injury in mice
por: Dai, Yan, et al.
Publicado: (2016)

MicroRNA-146a Improved Acute Lung Injury Induced by hepatic Ischemia-reperfusion Injury by Inhibiting PRDX1
por: Xu, Yiping, et al.
Publicado: (2023)

Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia
por: Ngwa, Conelius, et al.
Publicado: (2021)

IRAK-4 Inhibitors for Inflammation
por: Wang, Zhulun, et al.
Publicado: (2009)

Mice with miR-146a deficiency develop severe gouty arthritis via dysregulation of TRAF 6, IRAK 1 and NALP3 inflammasome
por: Zhang, Quan-Bo, et al.
Publicado: (2018)

MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways
por: Liu, Guang-Jie, et al.
Publicado: (2020)

MiR146a-loaded engineered exosomes released from silk fibroin patch promote diabetic wound healing by targeting IRAK1
por: Li, Qiankun, et al.
Publicado: (2023)

MicroRNA-146a negatively regulates inflammation via the IRAK1/TRAF6/NF-κB signaling pathway in dry eye
por: Han, Ruifang, et al.
Publicado: (2023)

The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists
por: Vollmer, Stefan, et al.
Publicado: (2017)

Circular RNA Fbxl5 Regulates Cardiomyocyte Apoptosis During Ischemia Reperfusion Injury via Sponging microRNA-146a
por: Li, Dongjiu, et al.
Publicado: (2022)

Remote ischemic perconditioning attenuates ischemia/reperfusion‐induced downregulation of AQP2 in rat kidney
por: Kristensen, Marie Louise V., et al.
Publicado: (2016)

Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation
por: Li, Jun-Jie, et al.
Publicado: (2017)

Downregulation of Bmal1 Expression in Celiac Ganglia Protects against Hepatic Ischemia-Reperfusion Injury
por: Feng, Jiarui, et al.
Publicado: (2023)

Ischemia/Reperfusion Injury in Liver Surgery and Transplantation
por: Schemmer, Peter, et al.
Publicado: (2012)

miR-146a Attenuates Sepsis-Induced Myocardial Dysfunction by Suppressing IRAK1 and TRAF6 via Targeting ErbB4 Expression
por: An, Rui, et al.
Publicado: (2018)

miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway
por: Liu, Yi-Nan, et al.
Publicado: (2020)

MicroRNA-146a inhibits NF-κB activation and pro-inflammatory cytokine production by regulating IRAK1 expression in THP-1 cells
por: Zhou, Chunlei, et al.
Publicado: (2019)

IRAK1: oncotarget in MDS and AML
por: Beverly, Levi J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ui2e4b61igpi8upv3ofs9iuck9