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Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease

Pneumococcal pili have been shown to influence pneumococcal colonization, disease development, and the inflammatory response in mice. The role of the pilus-associated RrgA adhesin in pneumococcal interactions with murine and human macrophages was investigated. Expression of pili with RrgA enhanced t...

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Detalles Bibliográficos
Autores principales:	Orrskog, Sofia, Rounioja, Samuli, Spadafina, Tiziana, Gallotta, Marilena, Norman, Martin, Hentrich, Karina, Fälker, Stefan, Ygberg-Eriksson, Sofia, Hasenberg, Mike, Johansson, Björn, Uotila, Liisa M., Gahmberg, Carl G., Barocchi, Michèle, Gunzer, Matthias, Normark, Staffan, Henriques-Normark, Birgitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531807/ https://www.ncbi.nlm.nih.gov/pubmed/23269830 http://dx.doi.org/10.1128/mBio.00535-12

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