Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting

Roughly one third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the bacterial plasma membrane(1). The proper localization of these proteins is mediated by a universally conserved protein targeting machinery, the signal recognition particle (SRP), which recognizes...

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Detalles Bibliográficos
Autores principales: Shen, Kuang, Arslan, Sinan, Akopian, David, Ha, Taekjip, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531814/
https://www.ncbi.nlm.nih.gov/pubmed/23235881
http://dx.doi.org/10.1038/nature11726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531814/
https://www.ncbi.nlm.nih.gov/pubmed/23235881
http://dx.doi.org/10.1038/nature11726

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