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Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting
Roughly one third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the bacterial plasma membrane(1). The proper localization of these proteins is mediated by a universally conserved protein targeting machinery, the signal recognition particle (SRP), which recognizes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531814/ https://www.ncbi.nlm.nih.gov/pubmed/23235881 http://dx.doi.org/10.1038/nature11726 |