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Lysosomal Rerouting of Hsp70 Trafficking as a Potential Immune Activating Tool for Targeting Melanoma
Tumor specific cell surface localization and release of the stress inducible heat shock protein 70 (Hsp70) stimulate the immune system against cancer cells. A key immune stimulatory function of tumor-derived Hsp70 has been exemplified with the murine melanoma cell model, B16 overexpressing exogenous...
Autores principales: | Juhász, Kata, Thuenauer, Roland, Spachinger, Andrea, Duda, Ernő, Horváth, Ibolya, Vígh, László, Sonnleitner, Alois, Balogi, Zsolt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531874/ https://www.ncbi.nlm.nih.gov/pubmed/22920897 http://dx.doi.org/10.2174/138161213804143644 |
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