Role of superoxide–nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

Mice lacking Cu,Zn superoxide dismutase (SOD1) show accelerated, age-related loss of muscle mass. Lack of SOD1 may lead to increased superoxide, reduced nitric oxide (NO), and increased peroxynitrite, each of which could initiate muscle fiber loss. Single muscle fibers from flexor digitorum brevis o...

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Detalles Bibliográficos
Autores principales: Sakellariou, Giorgos K, Pye, Deborah, Vasilaki, Aphrodite, Zibrik, Lea, Palomero, Jesus, Kabayo, Tabitha, McArdle, Francis, Van Remmen, Holly, Richardson, Arlan, Tidball, James G, McArdle, Anne, Jackson, Malcolm J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531889/
https://www.ncbi.nlm.nih.gov/pubmed/21443684
http://dx.doi.org/10.1111/j.1474-9726.2011.00709.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531889/
https://www.ncbi.nlm.nih.gov/pubmed/21443684
http://dx.doi.org/10.1111/j.1474-9726.2011.00709.x

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