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Successful Treatment of Scleredema Diabeticorum by Combining Local PUVA and Colchicine: A Case Report

Scleredema is a rare condition of unknown pathogenesis. It is classically divided into three types, based on its association with postinfection (usually streptococcal), monoclonal gammopathy and diabetes mellitus (scleredema diabeticorum). Scleredema diabeticorum often has a subtle onset, persistent...

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Detalles Bibliográficos
Autores principales: Kokpol, Chayada, Rajatanavin, Natta, Rattanakemakorn, Ploysyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531936/
https://www.ncbi.nlm.nih.gov/pubmed/23275772
http://dx.doi.org/10.1159/000345712
Descripción
Sumario:Scleredema is a rare condition of unknown pathogenesis. It is classically divided into three types, based on its association with postinfection (usually streptococcal), monoclonal gammopathy and diabetes mellitus (scleredema diabeticorum). Scleredema diabeticorum often has a subtle onset, persistent involvement and is refractory to therapies. Numerous therapies have been tried, with mixed and inconsistent results. We report herein a case of scleredema diabeticorum that was successfully treated by combining local PUVA with colchicine.