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Novel homodimer model of the β-adrenergic receptor in complex with free fatty acids and cholesterol: first-principles calculation studies

We propose a theoretical novel homodimer model of the β- adrenergic receptor (βAR) in complex with a heterogeneous mixture of free fatty acids (FFAs) and cholesterol based on first-principles calculations. We used the density-functional-based tight binding with dispersion (DFTB-D) method, which accu...

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Detalles Bibliográficos
Autores principales:	Nakano, Yuka, Watanabe, Yasuo, Ito, Yoshihiko, Yamada, Shizuo, Tokiwa, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2012
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532008/ https://www.ncbi.nlm.nih.gov/pubmed/23275728 http://dx.doi.org/10.6026/97320630081245

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