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Molecular and Cellular Response Profiles Induced by the TLR4 Agonist-Based Adjuvant Glucopyranosyl Lipid A

BACKGROUND: Toll-like receptor (TLR)4 agonists are known potent immunostimulatory compounds. These compounds can be formulated as part of novel adjuvants to enhance vaccine medicated immune responses. However, the contribution of the formulation to the innate in vivo activity of TLR4 agonist compoun...

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Detalles Bibliográficos
Autores principales: Lambert, Stacie L., Yang, Chin-Fen, Liu, Zheng, Sweetwood, Rosemary, Zhao, Jackie, Cheng, Lily, Jin, Hong, Woo, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532059/
https://www.ncbi.nlm.nih.gov/pubmed/23284726
http://dx.doi.org/10.1371/journal.pone.0051618