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Molecular and Cellular Response Profiles Induced by the TLR4 Agonist-Based Adjuvant Glucopyranosyl Lipid A
BACKGROUND: Toll-like receptor (TLR)4 agonists are known potent immunostimulatory compounds. These compounds can be formulated as part of novel adjuvants to enhance vaccine medicated immune responses. However, the contribution of the formulation to the innate in vivo activity of TLR4 agonist compoun...
Autores principales: | Lambert, Stacie L., Yang, Chin-Fen, Liu, Zheng, Sweetwood, Rosemary, Zhao, Jackie, Cheng, Lily, Jin, Hong, Woo, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532059/ https://www.ncbi.nlm.nih.gov/pubmed/23284726 http://dx.doi.org/10.1371/journal.pone.0051618 |
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