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Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases
Nt-acetylation is among the most common protein modifications in eukaryotes. Although thought for a long time to protect proteins from degradation, the role of Nt-acetylation is still debated. It is catalyzed by enzymes called N-terminal acetyltransferases (NATs). In eukaryotes, several NATs, compos...
Autores principales: | Grauffel, Cédric, Abboud, Angèle, Liszczak, Glen, Marmorstein, Ronen, Arnesen, Thomas, Reuter, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532069/ https://www.ncbi.nlm.nih.gov/pubmed/23285125 http://dx.doi.org/10.1371/journal.pone.0052642 |
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