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Ventilation Defect Formation in Healthy and Asthma Subjects Is Determined by Lung Inflation
BACKGROUND: Imaging studies have demonstrated that ventilation during bronchoconstriction in subjects with asthma is patchy with large ventilation defective areas (Vdefs). Based on a theoretical model, we postulated that during bronchoconstriction, as smooth muscle force activation increases, a patc...
Autores principales: | Harris, R. Scott, Fujii-Rios, Hanae, Winkler, Tilo, Musch, Guido, Vidal Melo, Marcos F., Venegas, José G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532117/ https://www.ncbi.nlm.nih.gov/pubmed/23285270 http://dx.doi.org/10.1371/journal.pone.0053216 |
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