2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models

BACKGROUND: The 2009 pandemic H1N1 influenza virus emerged in swine and quickly became a major global health threat. In mouse, non human primate, and swine infection models, the pH1N1 virus efficiently replicates in the lung and induces pro-inflammatory host responses; however, whether similar or di...

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Detalles Bibliográficos
Autores principales: Go, Jennifer T, Belisle, Sarah E, Tchitchek, Nicolas, Tumpey, Terrence M, Ma, Wenjun, Richt, Juergen A, Safronetz, David, Feldmann, Heinz, Katze, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532173/
https://www.ncbi.nlm.nih.gov/pubmed/23153050
http://dx.doi.org/10.1186/1471-2164-13-627

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