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Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability
BACKGROUND: LEF1/TCF transcription factors and their activator β-catenin are effectors of the canonical Wnt pathway. Although Wnt/β-catenin signaling has been implicated in neurodegenerative and psychiatric disorders, its possible role in the adult brain remains enigmatic. To address this issue, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532193/ https://www.ncbi.nlm.nih.gov/pubmed/23157480 http://dx.doi.org/10.1186/1471-2164-13-635 |