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Cancer Progression Mediated by Horizontal Gene Transfer in an In Vivo Model

It is known that cancer progresses by vertical gene transfer, but this paradigm ignores that DNA circulates in higher organisms and that it is biologically active upon its uptake by recipient cells. Here we confirm previous observations on the ability of cell-free DNA to induce in vitro cell transfo...

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Detalles Bibliográficos
Autores principales: Trejo-Becerril, Catalina, Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Anker, Philippe, Herrera-Goepfert, Roberto, Medina-Velázquez, Luis A., Hidalgo-Miranda, Alfredo, Pérez-Montiel, Delia, Chávez-Blanco, Alma, Cruz-Velázquez, Judith, Díaz-Chávez, José, Gaxiola, Miguel, Dueñas-González, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532306/
https://www.ncbi.nlm.nih.gov/pubmed/23285175
http://dx.doi.org/10.1371/journal.pone.0052754