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Cancer Progression Mediated by Horizontal Gene Transfer in an In Vivo Model
It is known that cancer progresses by vertical gene transfer, but this paradigm ignores that DNA circulates in higher organisms and that it is biologically active upon its uptake by recipient cells. Here we confirm previous observations on the ability of cell-free DNA to induce in vitro cell transfo...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532306/ https://www.ncbi.nlm.nih.gov/pubmed/23285175 http://dx.doi.org/10.1371/journal.pone.0052754 |