Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

BACKGROUND: Detailed and systematic understanding of the biological effects of millions of available compounds on living cells is a significant challenge. As most compounds impact multiple targets and pathways, traditional methods for analyzing structure-function relationships are not comprehensive...

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Detalles Bibliográficos
Autores principales: Khan, Suleiman A, Faisal, Ali, Mpindi, John Patrick, Parkkinen, Juuso A, Kalliokoski, Tuomo, Poso, Antti, Kallioniemi, Olli P, Wennerberg, Krister, Kaski, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532323/
https://www.ncbi.nlm.nih.gov/pubmed/22646858
http://dx.doi.org/10.1186/1471-2105-13-112

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