HIV Protease Inhibitors Do Not Cause the Accumulation of Prelamin A in PBMCs from Patients Receiving First Line Therapy: The ANRS EP45 “Aging” Study

BACKGROUND: The ANRS EP45 “Aging” study investigates the cellular mechanisms involved in the accelerated aging of HIV-1 infected and treated patients. The present report focuses on lamin A processing, a pathway known to be altered in systemic genetic progeroid syndromes. METHODS: 35 HIV-1 infected p...

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Detalles Bibliográficos
Autores principales: Perrin, Sophie, Cremer, Jonathan, Faucher, Olivia, Reynes, Jacques, Dellamonica, Pierre, Micallef, Joëlle, Solas, Caroline, Lacarelle, Bruno, Stretti, Charlotte, Kaspi, Elise, Robaglia-Schlupp, Andrée, Tamalet, Corine Nicolino-Brunet Catherine, Lévy, Nicolas, Poizot-Martin, Isabelle, Cau, Pierre, Roll, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532351/
https://www.ncbi.nlm.nih.gov/pubmed/23285253
http://dx.doi.org/10.1371/journal.pone.0053035

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